Rs. Pippalla et al., INTERRELATIONSHIPS OF QUALITY-OF-LIFE, COMPLIANCE, CLINICAL OUTCOMES AND LIFE SATISFACTION - A CROSS-SECTIONAL STUDY ON HYPERTENSIVE GERIATRICS, Journal of clinical pharmacy and therapeutics, 22(5-6), 1997, pp. 357-369
Objective: (i) To assess quality of life (QoL) profiles in hypertensiv
e geriatrics with SF-36; (ii) to assess the compliance of geriatrics t
o medications; (iii) to estimate clinical outcomes (reduction in systo
lic and diastolic blood pressure); (iv) to assess life satisfaction an
d (v) to explore the interrelationships of QoL, compliance, clinical o
utcomes and life satisfaction in hypertensive geriatrics. Method: Fift
y-nine hypertensive geriatric patients in cardiology and 65 Plus clini
cs in West Virginia Hospitals were studied. Results: Age showed a sign
ificant negative correlation with physical functioning (r=0 339, P les
s than or equal to 0.0127) and physical role (r=0.335, P less than or
equal to 0.0148). The physical role facet of SF-36 is correlated with
life satisfaction in geriatrics (r=0.316, P less than or equal to 0.02
19). A regression analysis (backward stepwise) not including bodily pa
in (Br) and general health (CH) resulted in a model explaining 22.3% o
f variance (n= 54, F=2.252, P less than or equal to 0.0543). Physical
role (P less than or equal to 0.0084) and mental health facets (P less
than or equal to 0.0184) of SF-36 emerged as the predictors of life s
atisfaction in elderly hypertensive patients. Emotional role functioni
ng (P less than or equal to 0.0257) and social functioning (P less tha
n or equal to 0.0033) scores predicted levels of diastolic blood press
ure in elderly hypertensive patients. However, all eight concepts of S
F-36 failed to predict compliance behaviour in geriatrics (n=53, P les
s than or equal to 0.6913, R-2=0.110).