Ll. Steiner et al., 3 NEW DP ALLELES IDENTIFIED IN SUB-SAHARAN AFRICA - DPB1-ASTERISK-7401, DPA1-ASTERISK-02013, AND DPA1-ASTERISK-0302, Tissue antigens, 51(6), 1998, pp. 653-657
HLA-DP genotyping of over 400 individuals from sub-Saharan Africa iden
tified three new DP alleles: DPB17401, DPA1*02013, and DPA1*0302. DNA
sequencing confirmed that DPB17401, found in one individual, is a no
vel combination oi previously described sequence motifs in the six var
iable regions of DPB1, DPA102013, found in one individual, is identic
al to DPA102012 except for two silent substitutions, a T to C transit
ion in codon 37, and an A to G transition in codon 38. DPA10302, iden
tified in seven individuals, is identical to DPA10301 except for a C
to T transition at the second position of codon 66. The identification
of these novel alleles brings the total number of reported DPB1 allel
es to 77 and DPA1 alleles to 11.