EFFECTIVENESS OF A NEW ANTIMICROBIAL EMOLLIENT IN THE MANAGEMENT OF ECZEMA DERMATITIS/

Authors
Citation
M. Whitefield, EFFECTIVENESS OF A NEW ANTIMICROBIAL EMOLLIENT IN THE MANAGEMENT OF ECZEMA DERMATITIS/, Journal of dermatological treatment, 9(2), 1998, pp. 103-109
Citations number
21
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
09546634
Volume
9
Issue
2
Year of publication
1998
Pages
103 - 109
Database
ISI
SICI code
0954-6634(1998)9:2<103:EOANAE>2.0.ZU;2-H
Abstract
A new antimicrobial emollient (Dermol 500 Lotion) has been developed c ontaining the antiseptics benzalkonium chloride and chlorihexidine hyd rochloride. In vitro and in vivo studies have been performed to confir m its antimicrobial activity particularly against Staphylococcus aureu s, the bacterial species increasingly implicated in the colonization a nd secondary infection associated with eczema/dermatitus and its relat ed pruritus. Dermol 500 Lotion was also shown to have a more powerful antimicrobial effect than E45 Cream, a comparator bland but preserved emollient. In a clinical trial of children with atopic dermatitis, Der mol 500 Lotion was effective and well liked by the majority of patient s, especially when compared to previously used emollients.