K. Teranishi et al., CONVENIENT REGIOSELECTIVE MONO-2-O-SULFONATION OF CYCLOMALTOOCTAOSE, Bioscience, biotechnology, and biochemistry, 62(6), 1998, pp. 1249-1252
Regioselective mono-2-O-sulfonation of cyclomaltooctaose was convenien
tly achieved by using the combination of sulfonyl imidazole and molecu
lar sieves in DMF. In this reaction, no 3-O- or 6-O-sulfonation produc
ts were produced. The reactions do not require strict anhydrous or bas
ic conditions, or specific sulfonyl groups.