CCD79A EXPRESSION IN A CASE OF PLASMA-CELL LEUKEMIA

In the present report we analyzed the immunophenotype of the neoplasti c cells in a case of primary plasma cell leukemia (PCL). We performed simultaneous analysis of bone marrow and peripheral blood samples to i nvestigate minor phenotypic variations that could explain the tendency of a population to leave medullary compartments. No major differences were observed between the two populations. The phenotype of the malig nant clone was: CD38(+), CD138(+), CD19(-), CD56(+), CD117(-), CD33(+) CD44(+), CD49e(-), cCD79a(+) with positive cytoplasmic stain for re a nd IgG. Our findings expands the potential uses of cCD79a to cases of PCL with atypical morphology. (C) 1998 Elsevier Science Ltd. All right s reserved.