G. Drobinski et al., EFFECTS OF ULTRASOUND ENERGY ON FEMORAL A RTERIAL-OCCLUSION ANGIOGRAPHIC AND ANGIOSCOPIC RESULTS, Archives des maladies du coeur et des vaisseaux, 86(9), 1993, pp. 1331-1336
Ultrasonic energy has been shown to be able to disrupt atherosclerotic
plaques and thrombi- The authors used an ultrasonic angioplastic tech
nique developed by the group in 10 patients with a femoral arterial oc
clusion. The ultrasonic angioplasty was attempted before surgical bypa
ss using a 130 cm long titanium guide wire with a 0.8 mm diameter and
a round distal tip measuring 2 or 2.5 mm. Angiographic and angioscopic
examinations were performed before and after the procedure in 9 patie
nts. It was not possible to perform the angioplasty in 1 patient. Angi
oscopy showed that the proximal part of the occlusion consisted of ath
eromatous material in 3 cases and of thrombus in 6 cases. Angiography
showed complete restoration of flow in 4 cases ; distal flow was very
slow in 4 cases and no distal run-off was observed in 1 case- Angiosco
py showed residual stenosis at the site of entry in only 1 case. In 3
cases, the artery had no significant residual stenosis. In the other 5
patients residual stenosis was present and angioscopy showed persiste
nce of strands of fibrin and small thrombi. These results show that ul
trasonic angioplasty was capable of recanalising an occlusion in 9 out
of 10 patients with partial or total disruption of thrombi. At the pr
esent stage of development of this system, balloon angioplasty would b
e an essential complement in most cases in order to obtain normal flow
without significant residual stenosis. The manoeuvrability of the gui
de wire and the relatively small size of the round distal tip explain
why not all the thrombi could be treated. When these problems are solv
ed, ultrasonic angioplasty could become a useful tool because of its m
echanical effects and its ability to disrupt clots.