M. Sugiyama et Y. Atomi, ANOMALOUS PANCREATICOBILIARY JUNCTION WITHOUT CONGENITAL CHOLEDOCHAL CYST, British Journal of Surgery, 85(7), 1998, pp. 911-916
Background Anomalous pancreaticobiliary junction (APBJ) without congen
ital choledochal cyst (CCC) carries a high risk of gallbladder carcino
ma development. The aim of this study was to obtain information allowi
ng early diagnosis and appropriate management. Methods The clinical fe
atures, imaging findings and surgical outcome of 18 patients with APBJ
without CCC were analysed retrospectively. Results Fourteen patients
had symptoms, including those of acute pancreatitis (five patients). I
n 16 patients the gallbladder showed abnormalities, including carcinom
a (eight) and mucosal hyperplasia (11). Ultrasonography detected gallb
ladder carcinoma with 100 per cent sensitivity and mucosal hyperplasia
with 91 per cent sensitivity. A long common channel was demonstrated
by endoscopic retrograde cholangiopancreatography (ERCP) in all patien
ts, endoscopic ultrasonography in nine of ten, and magnetic resonance
cholangiopancreatography (MRCP) in five of five. Five of eight patient
s with gallbladder carcinoma underwent extended cholecystectomy with b
ile duct excision. Three patients with cancer and eight with no cancer
had cholecystectomy alone. None developed bile duct carcinoma or acut
e pancreatitis after operation. All patients without malignancy remain
ed asymptomatic for a mean follow-up period of 4.7 years. Conclusion P
rophylactic cholecystectomy is recommended for patients with APBJ with
out CCC. For early diagnosis of APBJ, gallbladder abnormalities on ult
rasonography or acute pancreatitis of unknown aetiology should prompt
further investigation with ERCP or less invasive imaging modalities su
ch as endoscopic ultrasonography and MRCP.