Background This was a retrospective review of the long-term results of
femorotibial bypass using autologous vein and polytetrafluoroethylene
(PTFE) over 24 years. Methods Some 518 patients who underwent 635 fem
orotibial bypass grafts were studied. Outcome measures analysed includ
ed primary and secondary graft patency, limb salvage rates and death.
Results Overall primary and secondary graft patencies were 62 and 67 p
er cent respectively at 12 months, and 44 and 48 per cent at 24 months
. For vein grafts, the primary and secondary patencies were 63 and 66
per cent at 12 months, and 54 and 56 per cent at 24 months. For PTFE g
rafts, the primary and secondary patencies were 48 and 54 per cent at
12 months, and 31 and 37 per cent at 24 months. Limb salvage and patie
nt survival rates were 81 and 84 per cent at 12 months, and 73 and 74
per cent at 24 months. Primary and secondary graft patencies fur vein
were significantly better than for PTFE (P = 00001). There was no diff
erence in patency between reversed and in situ grafts. Conclusion Femo
rotibial bypass can produce excellent lone-term results. Vein remains
the conduit of choice but in the absence of vein acceptable results ca
n bce achieved with PTFE.