PRENATAL MRI DIAGNOSIS OF CORPUS-CALLOSUM AGENESIS - STUDY OF 20 CASES WITH PATHOLOGICAL COMPARISONS

Twenty prenatal MR studies of corpus callosum agenesis were retrospect ively studied and compared with neuropathologic examinations (18) or p ostnatal imaging (2). Corpus callosum agenesis were either complete (1 4) or partial (6). Positive diagnosis was made in 19 cases/20. The dia gnosis of ''isolated'' or ''associated'' corpus callosum agenesis was assessed in 11 cases/15. MR depicted 15 of the 33 associated neurologi c abnormalities. Prenatal MR is a valuable complementary technique for the diagnosis of corpus callosum agenesis when sonography is doubtful . MR could improve prognosis evaluation, since it enables depiction of associated abnormalities, notably gyral abnormalities, posterior foss a malformations, and intra-cranial cysts. MR images prove to be useful before neuropathologic examinations