H. Abe et al., TREATMENT OF MALIGNANT NEUROCARDIOGENIC VASOVAGAL SYNCOPE WITH A RATEDROP ALGORITHM IN DUAL-CHAMBER CARDIAC PACING, PACE, 21(7), 1998, pp. 1473-1475
A 29-year-old man with malignant vasovagal syncope presented with epis
odes of abrupt loss of consciousness associated with an aura, totaling
more than 10 episodes over 3 months. Holter monitoring showed cardiac
arrest with a duration of 15 seconds. Oral propranolol and disopyrami
de therapy failed to prevent the syncope. A dual chamber pacemaker wit
h a rate drop response algorithm successfully prevented the syncope bu
t not the aura. There may be multifactors involved in the mechanism of
this syndrome. The patient has returned to a normal active life. This
rate drop algorithm is an effective therapy for the prevention of syn
cope in malignant vasovagal syncope.