Adenoid basal carcinomas of the cervix, although rare, have been descr
ibed. We report a rare ease of adenoid basal carcinoma of the vagina.
A 64-year-old patient with persistent ASCUS on cytologic screening was
found to have a 2.5-cm lesion protruding from the right vaginal sidew
all. LEEP excision was performed. A second 0.5-cm lesion distal to the
primary tumor site was subsequently excised by LEEP. Both specimens w
ere determined to be adenoid basal carcinomas of the vagina. The patie
nt is presently without evidence for recurrent cancer 33 months after
primary tumor resection. This case demonstrates pathologic and clinica
l similarities to adenoid basal carcinoma of the cervix. Adenoid basal
carcinomas are less aggressive than adenocarcinomas or adenoid cystic
carcinomas of the cervix and have been adequately treated with nonrad
ical surgery such as conization, trachelectomy, or total abdominal hys
terectomy. Our experience suggests that adenoid basal carcinoma of the
vagina also may be treated with conservative surgical excision withou
t need for radical vaginectomy or radiation therapy.