Cj. Sutherland et al., A COMPARISON OF INTRAMUSCULAR TENOXICAM WITH INTRAMUSCULAR MORPHINE FOR PAIN RELIEF FOLLOWING TONSILLECTOMY IN CHILDREN, Paediatric anaesthesia, 8(4), 1998, pp. 321-324
A double blind trial was conducted to evaluate the analgesic efficacy
of intramuscular tenoxicam for pain relief following tonsillectomy in
children. Fifty children, aged 3-10 years, were randomly allocated to
receive intramuscular tenoxicam 0.75 mg.kg(-1) or intramuscular morphi
ne sulphate 0.2 mg.kg(-1) after induction of anaesthesia. Although the
tenoxicam group required significantly more postoperative morphine (m
ean 57.8 mu g.kg(-1) compared with 26.9 mu g.kg(-1), P = 0.025), the t
otal morphine dose was significantly reduced after tenoxicam (57.8 mu
g.kg(-1) compared with 226.9 mu g.kg(-1) P<0.0001). There was no diffe
rence between the quality of analgesia after discharge from recovery.
The incidence of postoperative vomiting was significantly reduced afte
r tenoxicam (20%) compared with morphine (71%).