P. Gastmeier et al., DIAGNOSTIC TRAINING IN THE SURVEILLANCE O F NOSOCOMIAL INFECTIONS - WHAT IS FEASIBLE AND USEFUL, Zentralblatt fur Hygiene und Umweltmedizin, 201(2), 1998, pp. 153-166
The data of surveillance of nosocomial infections are used as clinical
indicators of quality. Their diagnosis must therefore be accurate. On
e hundred medical records from surgical and intensive care patients we
re used to assess the accuracy of diagnosing nosocomial infections acc
ording to CDC definitions. All case histories included signs and sympt
oms of infection. There were 45 patients with a total of 60 nosocomial
infections (18 urinary tract infections, 18 surgical site infections,
11 lower respiratory tract infections and 13 other infection types).
After evaluating the medical records, 18 physicians independently deci
ded whether or not there was a nosocomial infection and, if so, the ty
pe of underlying infection. Their results were compared to the diagnos
is of two experienced physicians (gold standard). Twenty-five cases we
re assessed on each of four consecutive days and the results were disc
ussed with the experienced physicians on the following morning. The di
scussions of the first day may thus have been influenced by the result
s of the following days. Overall sensitivity was 85.4% (Cl-95 82.8-87.
8%) and overall specificity was 97.1% (Cl-95 95.8-98.0%). Among the mo
st common types of nosocomial infections, urinary tract infections had
the highest sensitivity (90.1%), followed by surgical site infections
(87.3%) and lower respiratory tract infections (85.8%). The specifici
ty for these types of infections was 98.2%, 98.9% and 99.5%, respectiv
ely. Although the method of investigation used does not fulfill the fo
rmal requirements of a validation study for diagnosing nosocomial infe
ctions, it seems useful for training in the diagnostics of nosocomial
infections or for intermittent evaluation of criteria before starting
surveillance activities. This method is useful for training the applic
ation of CDC definitions, particularly when the medical records are re
duced to case studies that include only the basic information on deter
mining the presence of a nosocomial infection in order to evaluate a l
arge number of suspected cases in a short period of time.