INVESTIGATIONS BY TIME-RESOLVED LASER-INDUCED FLUORESCENCE AND CAPILLARY-ELECTROPHORESIS OF THE URANYL-PHOSPHATE SPECIES - APPLICATION TO BLOOD-SERUM

An understanding of the speciation of uranium(VI) (uranyl ion, UO22+) in blood medium is very important for investigations of internal conta mination. Studies have been performed on the speciation of uranium(VI) in the presence of phosphate and blood serum using time-resolved lase r-induced fluorescence (TRLIF) and capillary electrophoresis (CE). By TRLIF it is possible to identify spectrally and temporally, by compari son with distribution curves calculated using data from the OECD datab ase, UO2H2PO4+, UO2HPO4 and UO2PO4- species. Results concerning the st udy of the uranium(VI)-blood plasma system are presented. CE has demon strated that it is possible to separate human gamma-, beta-, alpha(2)- , and alpha(1)-globulins and albumin in the presence of uranium(VI). ( C) 1998 Elsevier Science S.A.