Ej. Dodson et al., VALIDATION TOOLS - CAN THEY INDICATE THE INFORMATION-CONTENT OF MACROMOLECULAR CRYSTAL-STRUCTURES, Structure, 6(6), 1998, pp. 685-690
The explosive increase in the number of published three-dimensional st
ructures of macromolecules determined by X-ray analysis places a respo
nsibility on experimentalists, referees and curators of databases to e
nsure correspondence between the structure parameters and data. Valida
tion tools will evolve as more appropriate statistical techniques and
new information, such as that from proteins analysed at atomic resolut
ion, becomes available.