Multiple myeloma is a disseminated malignant neoplasm usually derived
from a single clone of plasma cells. Patients with myeloma have divers
e signs such as anemia, hypercalcemia, uremia, pathologic fractures, a
nd recurrent infections. Extraosseous manifestations are found in less
than 5% of patients with multiple myeloma. They can arise in any tiss
ue, and their presence has been associated with more aggressive diseas
e. The purpose of this essay is to illustrate the imaging findings of
extraosseous myeloma and heighten awareness of this unusual manifestat
ion of multiple myeloma.