Fj. Hornicek et al., LIMB SALVAGE WITH OSTEOARTICULAR ALLOGRAFTS AFTER RESECTION OF PROXIMAL TIBIA BONE-TUMORS, Clinical orthopaedics and related research, (352), 1998, pp. 179-186
A retrospective study was performed between 1980 and 1995 on 38 recipi
ents of proximal tibial allografts after wide resection of benign and
malignant tumors. Twenty-one (55%) patients experienced one or more co
mplications. Of the 26 patients who received chemotherapy, 15 (58%) ex
perienced one or more complications, whereas of the 12 patients who di
d not receive chemotherapy, six (50%) experienced one or more complica
tions, In the chemotherapy group, there were 12 (46%) fractures, four
(15%) infections, three (12%) nonunions, and four (15%) instabilities.
In the nonchemotherapy group there were three (25%) infections, two (
17%) fractures, one (8%) instability, and one (8%) nonunion, These com
plications were managed adequately with multiple subsequent surgical p
rocedures. Three patients underwent amputations for deep wound infecti
ons, Twelve (32%) patients underwent removal of the allograft, and the
limb was salvaged by reallografting or by total knee arthroplasty, Th
e results of both groups were 66% (25 of 38 patients) satisfactory (go
od or excellent), The chemotherapy group had a significantly higher in
cidence of fractures. All other complication rates and functional outc
omes were not significantly different between these groups.