K. Dittmer et al., REDUCED PATHOLOGICAL RETINAL FINDINGS AFT ER PORTOSYSTEMIC SHUNTING PROCEDURE IN CIRRHOTIC-PATIENTS, Der Ophthalmologe, 95(6), 1998, pp. 404-407
Background: In patients with advanced cirrhosis and portal hypertensio
n a portosystemic shunting procedure is often necessary. This induces
haemodynamic changes in the systemic circulation. The aim of this stud
y was to find out whether there were changes in the retinal perfusion
as well. Methods and patients: 17 patients with mainly ethyl-toxic cir
rhosis (13 male, 4 female; mean age 54 years, range 34-72 years) under
went ophthalmologic examination before and 3 months after TIPS (transj
ugular intrahepatic portosystemic stent shunt). Results: Before TIPS t
here were pathological findings in 11 patients: In five cases cottonwo
ol spots, in three cases discrete vessel abnormalities, in two cases s
mall intraretinal haemorrhages and in one case papilloedema. In all ca
ses these pathological findings were similar in both eyes. Three month
s after TIPS all these changes had completely disappeared or were at l
east considerably declining. Conclusions: The pathological findings in
patients with advanced cirrhosis were interpreted as signs of reduced
retinal perfusion. After a portosystemic shunting procedure signs of
recovery were seen.