FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS - IMPROVED NEURODEVELOPMENTAL OUTCOME AFTER BONE-MARROW TRANSPLANTATION

Authors
SHUPER A ATTIAS D KORNREICH L ZAIZOV R YANIV I
Citation
A. Shuper et al., FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS - IMPROVED NEURODEVELOPMENTAL OUTCOME AFTER BONE-MARROW TRANSPLANTATION, The Journal of pediatrics, 133(1), 1998, pp. 126-128
Citations number
11
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
133
Issue
1
Year of publication
1998
Pages
126 - 128
Database
ISI
SICI code
0022-3476(1998)133:1<126:FHL-IN>2.0.ZU;2-X
Abstract
A child with familial hemophagocytic lymphohistiocytosis (HLH) underwe nt allogeneic bone marrow transplantation (BMT) at age 5 months. At th at time he showed delayed psychomotor development, and computed tomogr aphy revealed diffuse calcification. After BMT, a gradual neurodevelop mental normalization was observed. The potential ability of BMT to rev erse neurodevelopmental deterioration in HLH should be considered.