Despite the advantages of compensation for resonance offset and B-1 in
homogeneity, adiabatic pulses are not yet in general use in high-resol
ution NMR, often because of the conception that these pulses require l
onger time or increased power to perform. We show that adiabatic pulse
s with tangential frequency sweeps and other frequency-modulation func
tions can be optimized to accomplish C-13 and H-1 broadband inversion
using pulse lengths of 192 and 64 mu s, respectively, at B-1 strengths
available with modern high-resolution probes. (C) 1998 Academic Press
.