VARICELLA-ZOSTER VIRUS-INFECTION ASSOCIATED WITH ACUTE LIVER-FAILURE

Although acute liver failure due to the varicella-zoster virus is rare , it is frequently fatal. Immunologic impairment is a significant pred isposing factor. Classic symptoms at presentation are rash, abdominal pain, and fever. After some days patients go on to develop full-blown liver failure. The diagnosis can be confirmed by histological examinat ion and electron microscopy with fluorescent staining, immunohistochem istry, and in situ hybridization of the liver. In cases of high suspic ion, acyclovir therapy should not be delayed.