Quantitative measurement of sound-induced discomfort and pain threshol
ds showed that migraineurs (n=65) were significantly more sensitive th
an headache-free controls (n=80), both during and outside attack (p <0
.0001). Patients tested with head pain had lower thresholds than those
tested without pain (p <0.01). Migraine with and without aura did not
differ as to sound sensitivity. There were no significant differences
in thresholds between the symptomatic and nonsymptomatic sides (p gre
ater than or equal to 0.78). Patients with unilateral headache or pain
of pulsating character were more sensitive than those with bilateral
headache or pressing pain (p <0.05). Phonophobia did not correlate sig
nificantly with duration, frequency, or severity of attacks. The main
results were in accordance with a questionnaire study concerning subje
ctive evaluation of sound sensitivity. Similarities between phonophobi
a and photophobia in migraine provide evidence that both phenomena sha
re a common pathophysiological mechanism in this condition.