Despite the accumulated evidence from clinical trials on the value of
lipid-lowering therapy in managing patients with established coronary
heart disease and risk factors and the availability of national guidel
ines for cholesterol-lowering in these patients, this knowledge has no
t yet been translated to clinical practice on a widespread basis. Nume
rous barriers exist that impede appropriate risk-factor management. Th
ese include patient barriers, physician barriers, barriers related to
the healthcare setting, and barriers in the community/society. Efforts
to provide appropriate risk-factor management will need to overcome t
hese barriers. Disease management systems that include preventive serv
ices are also needed.