I. Vilacosta et al., PENETRATING ATHEROSCLEROTIC AORTIC ULCER - DOCUMENTATION BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY, Journal of the American College of Cardiology, 32(1), 1998, pp. 83-89
Objectives. This study sought to describe the ability of transesophage
al echocardiography (TEE) to document the presence of penetrating athe
rosclerotic aortic ulcers and their complications. Background. TEE has
greatly enhanced our ability to assess patients with suspected aortic
disease. However, the utility of this technique in the diagnosis of p
enetrating atherosclerotic aortic ulcers is still undefined. Methods.
TEE was performed prospectively in 194 patients to evaluate aortic dis
ease. Twelve patients with the diagnosis of aortic ulcers or their com
plications were specifically studied. The diagnosis was confirmed by p
athologic studies in six patients and by an additional diagnostic tech
nique (angiography, computed tomography or magnetic resonance imaging)
in the other six. All 12 patients were hypertensive and presented wit
h chest or back pain; the mean age was 65 years (range 56 to 79). The
initial working diagnosis was acute aortic dissection in nine patients
. Aortic ulcers were located in the descending thoracic aorta in eight
patients, the aortic arch in two and the ascending aorta in two. Resu
lts. TEE could detect aortic ulcers or their complications in 10 patie
nts but failed to detect these lesions in the remaining 2 (1 with aort
ic ulcers in the distal ascending aorta and 1 with aortic ulcers in th
e aortic arch). In four patients, aortic ulcers were detected as a cal
cified focal outpouching of the aortic wall and were associated with c
oncomitant aneurysmal dilation of the aorta in two patients and with a
small localized intramural hematoma in one. TEE visualized a partiall
y thrombosed pseudoaneurysm complicating an aortic ulcer in the descen
ding thoracic aorta of two patients. Four patients had an aortic ulcer
complicated by a ''limited aortic dissection'' in the descending aort
a that could be detected by TEE. Five patients underwent operation, ho
because of aneurysmal dilation of the aorta and three because of aort
ic dissection; two patients died of aortic rupture; the remaining five
did well (11-month follow-up) without operation. Conclusions. Aortic
ulcers should be included in the differential diagnosis of chest or ba
ck pain, especially in elderly hypertensive patients. These ulcers and
their complications may be recognized by TEE. (C) 1998 by the America
n College of Cardiology.