SUBMOLECULAR RESOLUTION OF SINGLE MACROMOLECULES WITH ATOMIC-FORCE MICROSCOPY

Authors
CZAJKOWSKY DM SHAO ZF
Citation
Dm. Czajkowsky et Zf. Shao, SUBMOLECULAR RESOLUTION OF SINGLE MACROMOLECULES WITH ATOMIC-FORCE MICROSCOPY, FEBS letters, 430(1-2), 1998, pp. 51-54
Citations number
39
Categorie Soggetti
Biology,"Cell Biology",Biophysics
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
430
Issue
1-2
Year of publication
1998
Pages
51 - 54
Database
ISI
SICI code
0014-5793(1998)430:1-2<51:SROSMW>2.0.ZU;2-5
Abstract
The intrinsically high signal-to-noise ratio of atomic force microscop y (AFM) permits structural determination of individual macromolecules to, at times, subnanometer resolution directly from unprocessed images , avoiding the conditions and possible consequences of averaging over an ensemble of molecules. In this article, we will review some of the most recent achievements in imaging single macromolecules with AFM. (C ) 1998 Federation of European Biochemical Societies.