Objective: to examine the key determinants of pharmaco-epidemiology in
Australian nursing homes. Design: a cross-sectional survey of medicat
ion use in 998 residents in 15 nursing homes in Southern Queensland an
d Northern New South Wales, Results: the total, laxative, digoxin/diur
etic, benzodiazepine and psycholeptic medication prescribed and admini
stered to residents of nursing homes was affected to differing extents
by age and gender, the nursing home, resident functional disability a
nd medical practitioner. Resident Classification Instrument (RCI) cate
gory and nursing home were the dominant determinants for prescribing a
nd administration of the total drugs, laxative, benzodiazepine and psy
choleptic medications. In contrast, the resident use of digoxin and/or
diuretics was dependent on the resident age and on the functional dis
ability (RCI category) of the resident but not medical practitioner or
nursing home. Approximately 30% of medications were prescribed on a p
ro re nata (p.r.n.) basis and administered at the discretion of regist
ered nurses. Conclusion: nursing home culture is a major determinant o
f the variability in medication use between residents, particularly fo
r those medications often prescribed for p.r.n. use. The nursing home
does not account for variation in the use of digoxin and/or diuretics
which are prescribed on a non-discretionary basis.