E. Brambilla et al., CARIES PREVENTION DURING PREGNANCY - RESULTS OF A 30-MONTH STUDY, The Journal of the American Dental Association, 129(7), 1998, pp. 871-877
The purpose of this 30-month study was to explore the effectiveness of
a caries-preventive regimen in lowering the salivary mutans streptoco
cci level in pregnant women and, subsequently, in inhibiting the growt
h of these bacteria in their young children. Beginning at the end of t
he sixth month of pregnancy and continuing until delivery, subjects ri
nsed daily with 0.05 percent sodium fluoride and 0.12 percent chlorhex
idine. The authors monitored the salivary mutans streptococci levels d
uring the last six months of pregnancy and every six months thereafter
for 24 months. They also measured bacterial levels in the children ev
ery six months until they reached age 24 months. The results show that
treatment significantly reduced salivary mutans streptococci levels i
n mothers and delayed the colonization of bacteria in their children f
or about four months.