DEVELOPMENT OF SYNTHETIC VACCINES AGAINST ANTITUMOR AND HIV HAVING LIPID-A ANALOGS AS A SYNTHETIC IMMUNOADJUVANT

Authors
IKEDA K MIYAJIMA K ACHIWA K
Citation
K. Ikeda et al., DEVELOPMENT OF SYNTHETIC VACCINES AGAINST ANTITUMOR AND HIV HAVING LIPID-A ANALOGS AS A SYNTHETIC IMMUNOADJUVANT, Yuki Gosei Kagaku Kyokaishi, 56(7), 1998, pp. 567-580
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Yuki Gosei Kagaku Kyokaishi → ACNP
ISSN journal
00379980
Volume
56
Issue
7
Year of publication
1998
Pages
567 - 580
Database
ISI
SICI code
0037-9980(1998)56:7<567:DOSVAA>2.0.ZU;2-N
Abstract
This article describes our recent development of completely synthetic vaccines based on tumour- and HIV-associated carbohydrate and peptide antigens having N-tetradecanoyl L-seryl-beta-alanine-containing D-gluc osamine derivatives structurally related to lipid A as efficient synth etic immunoadjuvants.