A. Andreoli et al., ROLE OF ULTRASONOGRAPHY IN THE DIAGNOSIS OF POSTSURGICAL RECURRENCE OF CROHNS-DISEASE, The American journal of gastroenterology, 93(7), 1998, pp. 1117-1121
Objective: Ultrasonography is a valid tool in the diagnosis of Crohn's
disease, but its sensitivity, specificity, and overall accuracy in th
e diagnosis of postoperative recurrence are still not well established
, The aim of this study was to evaluate the accuracy of ultrasonograph
y compared with endoscopy in the diagnosis of postoperative recurrence
of Crohn's disease. Methods: Forty-seven patients resected for Crohn'
s ileitis were studied by ultrasonography and colonoscopy to detect po
ssible recurrence of the disease; 10 patients operated on for cancer o
f the right colon were used as controls. Six patients with Crohn's dis
ease were excluded from the study because of failure to endoscopically
reach the anastomosis; the remaining 41 patients had both ultra-sonog
raphy and colonoscopy over a period of 14 days. Sonographic recurrence
was defined as the presence of >5 mm thickness of the ileal wall. Res
ults: Sensitivity, specificity, and overall accuracy of ultrasonograph
y in diagnosis of postoperative recurrence were 81%, 86%, and 83% resp
ectively. Positive predictive value was 96% and negative predictive va
lue was 57%, Conclusion: This study is the first to assess the role of
ultrasonography in comparison with endoscopy in detecting Crohn's dis
ease recurrence after surgery. Our data suggest that ultra-sonography
should be used first in the case of clinical suspicion of Crohn's dise
ase recurrence, reserving ileocolonoscopy for negative or uncertain ca
ses. (C) 1998 by Am. Coll. of Gastroenterology.