A 14-year-old boy has been followed for 4 years with a rapidly growing
, recurrent area of fibrous dysplasia of the left maxilla and zygoma f
ollowing resection and bone grafting. Standing 190 cm tall, he was fou
nd to have elevated serum growth hormone levels and a pituitary adenom
a. His case appears to represent a postzygotic gene mutation of McCune
-Albright syndrome. It is possible that the elevated growth hormone le
vels are in part responsible for the rapid progression of the tumor.