Objective: To assess the usefulness of TRUS-guided aspiration and opac
ification of seminal tracts in the evaluation and management of patien
ts with ejaculatory duct obstruction (EDO). Methods: In 21 men who had
dilated seminal vesicles and/or midline cysts on TRUS, a mixture of c
ontrast media and indigocarmine was injected and then pelvic radiograp
hs were taken. Results: The diagnoses based on the findings of TRUS-gu
ided opacification were bilateral EDO in 9 patients, unilateral EDO in
1, and midline cyst with EDO in Ii. Midline cysts had communication w
ith seminal tracts in 7. Transurethral unroofing was performed in 12,
in all of whom blue color of the injected indigocarmine facilitated th
e surgical procedure. Conclusion: TRUS-guided opacification of the sem
inal tracts with a mixture of contrast media and indigocarmine may be
valuable in the evaluation and management of the patients with EDO.