STIMULATION OF CONIDIATION BY DERIVATIVES OF CAMP IN TRICHODERMA-VIRIDE

Derivatives of cyclic-3',5'-adenosine monophosphate, N-6,2'-O-dibutyry l-cAMP, 8-(chlorophenylthio)-cAMP and 8-bromoadenosine-cAMP added at 0 .1-10 mu mol/L concentrations into the growth medium have markedly sti mulated conidiation in Trichoderma viride. Their stimulatory effect on conidiation was best observed in colonies that were constantly kept i n the dark but was also marked in colonies illuminated by sub-saturati ng doses of light. The relative stimulation of conidiation depended no t only on the concentration of exogenous cyclic nucleotides but also o n the concentration of glucose in the medium. It was more pronounced i n glucose-rich media than in media where the concentration of the suga r was low. Concentrations of cAMP analogues equal to 50 mu mol/L and h igher inhibited the conidiation.