FLICKER NOISE IN BILAYER-LIPID MEMBRANES

For the first time, we observe long-living voltage fluctuations in a b ilayer membrane of diphytanoyl phosphatidylcholine held in current-cla mp conditions. These fluctuations follow an increase of the membrane c onductance due to the opening of hydrophilic pores induced by the tran smembrane voltage, a phenomenon called electroporation. The measured p ower spectrum for membranes under these conditions is proportional to the reciprocal of the frequency.