M. Habel et al., THE FIRST 1,10-DIAZA[2.2]METACYCLOPHANES - STRAINED MEDIUM MEMBERED HETEROCYCLES, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (7), 1998, pp. 1471-1477
the hypothesis that 7 is one of the most strained anti-hetera[2.2]meta
cyclophanes known. This is also evident from the H-1-NMR spectrum of 7
, which shows one of the strongest high field shifts for the intraannu
lar protons in comparison to other anti-[2.2]metacyclophanes.