An investigation was undertaken at a printing company into an apparent
ly high prevalence of trace dipstick hematuria discovered during routi
ne medical examinations. In both the printing employees (n = 225) and
a control group (n = 118) from other industries, the prevalence of hem
aturia exceeded that described in most previous reports (31% and 25%,
respectively, using the criterion of >12 glomerular red cells or >2 no
nglomerular red cells/mul of urine). No focus of abnormality was ident
ified within the printing plant and no association was identified betw
een reported exposure to potentially toxic substances and the degree o
f hematuria. An occupational hygiene inspection and medical follow-up
of selected workers did not reveal any significant abnormalities. The
limitations of available information concerning ''normal'' urinalysis
results suggests that hematuria may not be a useful test for the scree
ning of occupational groups at risk of bladder cancer.