NEW CHEMISTRY OF PYRROLIZIN-3-ONE - A CONCISE ROUTE TO 3,8-DIDEHYDROHELIOTRIDIN-5-ONE

Citation
H. Mcnab et C. Thornley, NEW CHEMISTRY OF PYRROLIZIN-3-ONE - A CONCISE ROUTE TO 3,8-DIDEHYDROHELIOTRIDIN-5-ONE, Journal of the Chemical Society, Chemical Communications, (20), 1993, pp. 1570-1571
Citations number
11
Categorie Soggetti
Chemistry
ISSN journal
00224936
Issue
20
Year of publication
1993
Pages
1570 - 1571
Database
ISI
SICI code
0022-4936(1993):20<1570:NCOP-A>2.0.ZU;2-E
Abstract
1-Substituted 1,2-dihydropyrrolizin-3-ones can be obtained from pyrrol izin-3-one 2 by conjugate nucleophilic addition or electrophilic addit ion reactions; the 1-chloro compound 9 obtained by the latter method i s used as a key intermediate in a six-step synthesis of the title comp ound 3 from 4-acetoxymethylpyridine-N-oxide.