In the confirmation of recurrences of genital herpes, patient defined
disease reactivation and virological data hold the scientific high gro
und. The influence of the psyche on recurrence rates and perception of
recurrences has been largely neglected and marginalised up to the pre
sent, possibly because research work in that area has been and continu
es to be of poor calibre. However, neglected psychological variables m
ay render otherwise relevant clinical trials uninterpretable. Psycholo
gical aspects of counselling before testing for serum herpes simplex t
ype 2 antibodies are also discussed.