EVALUATION OF PREGNANCY RATES AFTER INTRAUTERINE INSEMINATION ACCORDING TO INDICATION, AGE, AND SPERM PARAMETERS

Purpose: Our purpose was to evaluate intrauterine insemination results obtained in our clinic and identify prognostic factors for the chance of pregnancy. Methods: A retrospective study of data from 1989 to 199 6 was undertaken Only first attempts were included in this study, exce pt for the part on the cumulative pregnancy rates. Couples with either one-sided tubapathology hormonal dysfunction, idiopathic infertility or andrological indication were selected. All women were stimulated wi th clomiphene citrate. Five hundred sixty-six couples who underwent 17 63 cycles were included in the study. Results: The overall pregnancy r ate for first pregnancies was 6.9% per cycle and 21.4% per patient, Fo r first intrauterine insemination attempts this was 8.8% per cycle/pat ient, varying between 5.0% for andrological indication and 10.6% for t ubapathology, 10.0% for idiopatic indication, and 10.3% for hormonal i ndication. These differences were not significant. Age did not have a significant effect either although there were no pregnancies observed in women 40 years or older: The number of inseminated spermatozoa sign ificantly affected the pregnancy rate: <2 million, 4.6%, greater than or equal to 2 to <10 million, 3.9%; and greater than or equal to 10 mi llion, 11.3%. Conclusions: Unless semen characteristics are insufficie nt, intrauterine insemination is a useful treatment for infertile coup les.