TRANSIENT PSEUDOHYPOALDOSTERONISM IN OBSTRUCTIVE RENAL-DISEASE

The cases of two patients with transient pseudohypoaldosteronism due t o an up to this point unrecognized obstructive renal disease are repor ted. Both girls presented with a severe salt-losing episode in early i nfancy mimicking congenital adrenal hyperplasia, Extensive endocrinolo gic workup revealed markedly elevated plasma-aldosterone levels. Clini cal and laboratory data were consistent with transient pseudohypoaldos teronism. Sonographic and radiological investigation showed in both ch ildren a vesicoureteral reflux of differing grades, After therapy of t he electrolyte-imbalance and recovery, one of the children required su rgical treatment of vesicoureteral reflux.