P. Lavandhomme et M. Dekock, PRACTICAL GUIDELINES ON THE POSTOPERATIVE USE OF PATIENT-CONTROLLED ANALGESIA IN THE ELDERLY, Drugs & aging, 13(1), 1998, pp. 9-16
Inadequate pain control after surgery is associated with adverse outco
mes in elderly patients; for this reason, effective analgesia is an es
sential component of postoperative care in this patient group. However
, postoperative pain management is challenging in the elderly because
of concomitant disease states and physiological factors that can affec
t the pharmacodynamic and pharmacokinetic properties of analgesic drug
s. Patient-controlled analgesia (PCA) offers advantages over tradition
al intramuscular analgesia in this setting, because it provides the op
portunity to tailor therapy to the individual, as opposed to the avera
ge, patient. Morphine is the most widely used, and presently the most
suitable, drug for use in PCA in the elderly. Studies have indicated t
hat, after acute pain has been brought under control, PCA should be in
itiated at a dose of 1 or 1.5 mg per dose, with a lockout period of 5
to 7 min. Continuous background infusions of opioids are contraindicat
ed. Education of patients and healthcare professionals alike is necess
ary to optimise the utility of PCA in older patients. In addition, eve
ry effort should be made to avoid the development of postoperative con
fusion, as this is associated with an increased risk of inefficient pa
in relief and its deleterious consequences. In summary, close monitori
ng and evaluation of the patient throughout the perioperative period i
s required to ensure the appropriate and successful use of PCA in elde
rly patients.