HEMISPHERE ASYMMETRY IN PARASYMPATHETIC CONTROL OF THE HEART

Hemisphere asymmetry in the control of parasympathetic outflow to the sino-atrial node of the heart was studied in healthy human subjects us ing lateralized film presentation for selective sensory stimulation of the hemispheres and power spectral analysis of heart rate variability as a measure of vagal tone. There was a clear a,nd consistent left he misphere predominance in the control of parasympathetic modulation of cardiac activity which cannot be attributed to differences in emotiona l processing. Supplementing previous findings of our research group, t he present study indicates that control of autonomic cardiac activity at the level of the cerebral cortex seems to be characterized by a div ision of responsibility between both hemispheres, sympathetic activity being mainly controlled by the right hemisphere and parasympathetic a ctivity being under the left hemisphere's main control. (C) 1998 Elsev ier Science Ltd. All rights reserved.