Sk. Malhotra et al., EFFECT OF HALOTHANE EXPOSURE ON MOTOR-SKILLS AND MEMORY IN ANESTHETISTS, Indian journal of medical research. Section B: Biomedical research other than infectious diseases, 98, 1993, pp. 218-222
In a prospective study involving 24 anaesthesia residents, each reside
nt was assessed three times i.e., first as control group, not exposed
to anaesthesia at all; the second group in which the resident was expo
sed to anaesthesia while using controlled respiration with closed circ
uit without halothane (non-halothane group) and the third group in whi
ch they were exposed to anaesthesia using spontaneous respiration with
semiclosed circuit using halothane (halothane group). After each expo
sure of 3-4 h duration in each group, the resident was subjected to sp
ecific psychological tests to assess motor skills and memory. In the n
on-halothane group, a depression of motor skills by 5.51 per cent and
of memory by 17.14 per cent was observed. In the halothane group, the
reduction of motor skills was up to 27 per cent and of memory by 45 pe
r cent as compared to the control values. It is concluded that 3-4 h e
xposure to halothane (1.5-4%) obtunds the motor skills and memory in a
naesthetists.