REGIOSELECTIVE S-N-ALLYLIC TRANSPOSITION OF 3-ALLYLTHIO-1,2,4-TRIAZINE, A CONVENIENT ROUTE TO 2-METHYLTHIAZOLO-1,2,4-TRIAZINES

Authors
NOOSHABADI MA AGHAPOOR K TABARHEYDAR K HERAVI MM
Citation
Ma. Nooshabadi et al., REGIOSELECTIVE S-N-ALLYLIC TRANSPOSITION OF 3-ALLYLTHIO-1,2,4-TRIAZINE, A CONVENIENT ROUTE TO 2-METHYLTHIAZOLO-1,2,4-TRIAZINES, Indian Journal of Heterocyclic Chemistry, 7(4), 1998, pp. 301-302
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian Journal of Heterocyclic Chemistry → ACNP
ISSN journal
09711627
Volume
7
Issue
4
Year of publication
1998
Pages
301 - 302
Database
ISI
SICI code
0971-1627(1998)7:4<301:RSTO3>2.0.ZU;2-Z
Abstract
The facile and regioselective cyclization of 3-allylthio 6-methyl-1,2, 4-triazin-5(2H)one 2 to 2,3-diyhdro-3,6-dimethyl-1,2,4-triazin-5-one 3 has been performed by the catalytic action of H2SO4. The regioselecti ve Pd (II) salt catalyzed Claisen rearrangement of 2 has been carried out to obtain the corresponding 4N-allyl derivative 5. The latter was cyclized by acid catalysis to afford 2-substituted thiazolo triazine 7 .