M. Yamada et al., GASTRIC ANTRAL VASCULAR ECTASIA SUCCESSFULLY TREATED BY ENDOSCOPIC ELECTROCOAGULATION, Journal of gastroenterology, 33(4), 1998, pp. 546-549
We report two cirrhotic patients with gastric antral vascular ectasia
(GAVE) in whom chronic blood loss presented a major problem. Case 1, a
69-year-old man, had alcoholic liver cirrhosis. and case 21 a 75-year
-old woman, had liver cirrhosis associated with hepatitis C virus. The
patients required repeated blood transfusions but still exhibited per
sistent anemia. On upper gastrointestinal endoscopy, both patients sho
wed esophageal varices without stigmata of bleeding or red color signs
and presented with a characteristic antral appearance so distinctive
as to be diagnostic; diffuse erythemas consisting of ectatic and tortu
ous capillaries throughout the antrum. Endoscopic electrocoagulation t
reatment with a monopolar probe was effective for controlling blood lo
ss from GAVE. The patients tolerated the procedure well and there were
no resultant complications. Several sessions of the treatment resulte
d in eradication of almost all the vascular lesions, negative fecal oc
cult blood test results, and marked alleviation of their anemia withou
t further treatment. Endoscopic electrocoagulation is suggested to be
a safe, non-invasive, and effective treatment for blood loss from GAVE
, especially in patients with liver cirrhosis in whom surgery carries
an increased risk.