PORT SITE METASTASES AND RECURRENCE AFTER LAPAROSCOPIC COLECTOMY - A RANDOMIZED TRIAL

Background: This study was performed to prospectively assess the impac t of the laparoscopic approach to the patterns of port site metastases (PSM) and recurrence rate (RR) of resected colon carcinomas as compar ed with conventional colectomies. Methods: All patients were included in a prospective randomized trial comparing laparoscopic-assisted cole ctomy (LAC) versus open colectomy (OC) for colon cancer. The randomiza tion was stratified for localization of the lesion. Patients with meta stasic disease at the time of the surgery were excluded. Follow-up in the outpatient clinic was done every 3 months for a minimum of 12 mont hs. Endpoints for the study were metastasis at port site and laparotom y incision as well as recurrence rate. Results: Of 91 segmental colect omies performed from November 1993 to January 1996, there were 44 LAC and 47 OC. Patient data were similar in both groups (age, sex, Dukes s tage, type of operation). Mean follow-up was 21.4 months, with a range of 13 to 41 months. There were no wounds or PSM in those series. RR w as similar for both groups. For LAG, it was five of 31 (16.1%); for OC , it was six of 40 (15%). Conclusions: The laparoscopic approach has a recurrence rate similar to that for open procedures for colon cancer. However, additional follow-up of these patients is needed before we c an determine whether or not the laparoscopic approach influences overa ll survival.