Endoscopic ultrasound (EUS) is an emerging technique that can be used
to visualize lesions in or adjacent to the gastrointestinal tract. We
performed a review of current indications and capabilities of endoscop
ic ultrasound. EUS provides diagnostic information on submucosal lesio
ns of the gastrointestinal tract. It is the most accurate method for l
ocal staging of esophageal and rectal cancer. It appears to be more se
nsitive in detecting common bile duct stones than endoscopic retrograd
e cholangiopancreatography. Furthermore, its use avoids the risk of pa
ncreatitis. Lesions deep to the gastrointestinal tract, such as medias
tinal nodes or pancreatic lesions, can be biopsied through the EUS end
oscope. New therapeutic uses of EUS include aid in endoscopic drainage
of pancreatic pseudocysts and celiac axis neurolysis for the treatmen
t of pain from pancreatic cancer. EUS offers many new diagnostic capab
ilities to visualize and biopsy lesions in or adjacent to the gastroin
testinal tract. Therapeutic uses are also emerging for this new techni
que.