Qz. Ding et Jw. Lown, SYNTHESIS OF THE PYRIDINO[4,3,2-DE]QUINOLINE NUCLEUS - A DERIVATIVE OF THE DISCORHABDIN ALKALOIDS, Heterocyclic communications, 4(2), 1998, pp. 125-129
A novel method of synthesis from catechol of the pyridino[4,3,2-de]qui
noline nucleus structurally related to discorhabdin alkaloids is devel
oped. Proof of the position of the chlorine substituent in the key chl
orination step was obtained by x-ray diffraction analysis of an interm
ediate (8) under bar.