BACKGROUND: Electrocautery has been postulated as a factor in the risk
of seroma formation after mastectomy. METHODS: Eighty consecutive mas
tectomies in 74 patients were randomly assigned to dissection of the m
astectomy flaps with either scalpel (0 = 38) or electrocautery (0 = 42
). Total volume of fluid output through drains and aspirated from sero
mas was recorded. Other factors investigated included the type of drai
n utilized, estimated blood loss, and complications. RESULTS: Seromas
developed in 16 wounds in the electrocautery group compared with 5 in
the scalpel group (38% and 13%, respectively; P = 0.01). Other factors
with an independent risk for seroma included use of Jackson-Pratt dra
ins compared with Blake drains (P = 0.006), and lower estimated blood
loss (P = 0.006). No differences in characteristics of patients or in
other complications were noted. CONCLUSIONS: Use of electrocautery to
create skin flaps in mastectomy reduced blood loss but increased the r
ate of seroma formation. (C) 1998 by Excerpta Medica, Inc.