A theory for ultrasonic fragmentation of agglomerate particles suspend
ed in liquids is presented. Imploding cavitation bubbles rupture the a
gglomerates. An expression for the fragmentation rate as a function of
ultrasonic power and agglomerate size is derived. A sectional model f
or fragmentation is used to simulate the evolution of the particle siz
e distribution of silica and titania powders suspended in water. The f
ragmentation rate expression is evaluated by comparing simulated with
experimental size distributions at the self-preserving limit. The requ
ired time and energy for particle size reduction is calculated as a fu
nction of ultrasonic power input.