PAIN - NOCISTATIN SPELLS RELIEF

Authors
MARTIN WJ MALMBERG AB BASBAUM AI
Citation
Wj. Martin et al., PAIN - NOCISTATIN SPELLS RELIEF, Current biology, 8(15), 1998, pp. 525-527
Citations number
12
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
8
Issue
15
Year of publication
1998
Pages
525 - 527
Database
ISI
SICI code
0960-9822(1998)8:15<525:P-NSR>2.0.ZU;2-A
Abstract
Tissue or nerve injury can dramatically alter the transmission of sens ory stimuli by spinal cord neurons, so that a light touch produces pai n. The discovery that peptide products of prepronociceptin processing either facilitate or inhibit these mechanisms suggests novel approache s to treating these conditions.